The College of Education for Pure Sciences Discusses a Master’s Thesis on the Preparation and Characterization of Novel Pharmaceutical Nanoparticles
The Chemistry Department at the College of Education for Pure Sciences, University of Kerbala, discussed a Master’s thesis entitled “Preparation and Characterization of Novel Pharmaceutical Nanoparticles and Studying Their Potential to Inhibit Breast Cancer.”
The thesis was presented by student Zahraa Mahdi Saleh Al-Husseini, under the supervision of Prof. Dr. Mohammed Nadhim Bahjat.
The study aimed to prepare a novel linear copolymer and characterize it using FT-IR, 1H-NMR, AFM, TEM, XRD, and DSC techniques. It also aimed to prepare drug-derived copolymers by reacting them with various drugs (ampicillin, theophylline, folic acid, and paracetamol), and characterize them using FT-IR and 1H-NM techniques. Furthermore, the study investigated some properties of the drug-derived linear copolymer compounds, such as solubility, drug release, and molecular docking.
The study concluded with the preparation and characterization of a linear copolymer nanocomposite using FT-IR, 1HNMR, AFM, XRD, TEM, and DSC techniques. Novel linear copolymer nanocomposites were then prepared from pharmaceutical polymers and characterized using FT-IR and 1HNMR techniques. Commonly used drugs were linked to these nanocomposites, and the resulting drug compounds were identified. Examples include ampicillin, theophylline, folic acid, and paracetamol.
The study recommended the preparation of novel drug compounds by establishing polymer-drug linkages. It also suggested the potential use of other drugs to extend drug shelf life and increase efficacy, particularly in chronic diseases requiring repeated daily doses. Furthermore, it highlighted the potential for reducing toxicity and targeting drug release to specific patient sites. The study also explored the nanoscale properties of some of the prepared pharmaceutical polymers and their veterinary applications.
