The College of Education for Pure Sciences Discusses a Doctoral Thesis on the Effect of Sepsis on Cardiac Biomarkers and a Study of Resistant Bacteria.
The College of Education for Pure Sciences Discusses a Doctoral Thesis on the Effect of Sepsis on Cardiac Biomarkers and a Study of Resistant Bacteria.
The College of Education for Pure Sciences Discusses a Doctoral Thesis on the Effect of Sepsis on Cardiac Biomarkers and a Study of Resistant Bacteria.
The Department of Biology at the College of Education for Pure Sciences at the University of Kerbala discussed a doctoral thesis entitled “The effect of sepsis on cardiac biomarkers and a study of resistant bacteria in heart patients in Kerbala.”
By student Sara Saeed Hassan Al-Rubaie under the supervision of Prof. Dr. Alaa Abdul-Hussein Karim.
The study aimed to identify the most common types of bacteria responsible for sepsis in heart failure patients, study their relationship to risk factors for heart failure, determine their sensitivity patterns to antibiotics, and determine the levels of various parameters affected by bacterial infection in heart failure patients.
The study concluded that the most common bacterial species found in isolates from infected heart failure patients was Staphylococcus hominis, and among infected patients, only Klebsiella pneumoniae was present. Most bacterial isolates were resistant to ciprofloxacin and gentamicin in the study groups, while vancomycin, linezolid, pefloxacin, and colistin were effective in most isolates. Levels of troponin, NT-proBNP, CNP, IMA, and sCD40L were elevated in heart failure patients.
The study recommended that blood cultures should be performed before administering antibiotics to individuals suspected of having sepsis to prevent the development of additional resistance. It also recommended studying the genes responsible for heart failure and studying the effect of heart failure on hormonal status. Close monitoring of vital signs and hematological parameters is essential in heart failure patients, especially during episodes of infection. Regular evaluation can also help in early detection of complications and guide therapeutic interventions.
