The College of Education for Pure Sciences Discusses a Master’s thesis entitled: “A Study of the Effect of the Aqueous and Alcoholic Extract of the Blackberry (Rubus plicatus) on Some Functional Parameters”
The Department of Biology at the College of Education for Pure Sciences at the University of Karbala discussed a master’s thesis entitled “A Study of the Effect of the Aqueous and Alcoholic Extract of the Blackberry (Rubus plicatus) on Some Functional Parameters and Histology of Some Parts of the Digestive System of Local Male Rabbits Induced by Therapeutic Hypothyroidism”
by student Zahraa Ali Habib under the supervision of Asst. Prof. Dr. Batool Abbas Hussein.
The thesis aimed to study digestive disorders and their current diseases, which may be caused by undiagnosed hypothyroidism, and delayed detection poses a significant risk. It also aimed to identify digestive disorders due to hypothyroidism and to understand the role of the raspberry (Rubus plicatus) in reducing its negative effects by: therapeutically inducing hypothyroidism and studying the concentration levels of thyroid hormones, including TSH, T3, T4, and Gastrin. Stomach.
The thesis concluded that treatment with carbimazole caused oxidative stress, manifested by a decrease in total antioxidant levels and an increase in MDA levels. Hypothyroidism induced by carbimazole resulted in hormonal, enzymatic, and biochemical changes. Furthermore, thyroid disorders led to histological changes in the liver, stomach, and duodenum.
The study recommended the use of aqueous extract of blackberry fruits as a preventative measure for patients with hypothyroidism prior to treatment to determine its effect. The aqueous extract should be nano-loaded and its effects on other organs should be observed. Further studies should be conducted on the aqueous extract to investigate its potential use as an antioxidant.
