Scientific Seminars Held for Graduate Students in the Department of Biology…
As part of the Department of Biology’ commitment to supporting the research of graduate students and enhancing the quality of their outputs, the Seminar and Discussion Committee organized a series of scientific seminars for doctoral student Ali Jabbar Abdullah, entitled “Molecular Detection of Polymorphisms in the p53 Codon 72 Gene and its Association with Prostate Cancer.”
This study aimed to detect polymorphisms in the P53codon72 gene, a tumor suppressor gene with a polymorphism whose genotypes are associated with disease development, particularly cancers such as prostate cancer. DNA was extracted from the blood of both study groups (patients and healthy individuals), and molecular detection of nucleotide polymorphisms in the studied genes was performed using Multiplex-PCR and PCR-RFLP techniques.
The study recommended the introduction of molecular testing as a means of early cancer detection in oncology centers at Iraqi hospitals. This would allow for the early detection of any damage to key cancer-causing genes, especially in individuals with risk factors. The study also recommended investigating other mutations or polymorphisms in the P53codon72 gene or other genes associated with prostate cancer using various molecular techniques. Furthermore, it recommended increasing research on genes encoding antioxidant and detoxifying enzymes to utilize this knowledge in diagnosis and treatment.
