The Department of Biology discusses a doctoral thesis on evaluating the protective role of the aqueous extract of Epimedium grandiflorum on some histological changes in the reproductive system of male albino rats treated with cisplatin

Discussion of a Doctoral Thesis


The Department of biology at the College of Education for Pure Sciences at the University of Karbala discussed a doctoral thesis entitled “Evaluation of the protective role of the aqueous extract of Epimedium grandiflorum on some histological changes in the reproductive system of male albino rats treated with cisplatin.” The thesis was presented by the student (Rasha Fadel Musa), under the supervision of Professor Dr. (Ashwaq Kazim Obaid)
The thesis aimed to evaluate the protective role of the aqueous extract of the horny goat weed plant (Epimedium grandiflorum) against histological and physiological changes in the reproductive system of male albino rats treated with cisplatin (Cp). The thesis also concluded that the aqueous extract of horny goat weed has a protective effect against changes in the tissues of the male reproductive system, its effectiveness as an antioxidant, its ability to reduce free radicals, reduce oxidative stress, protect testicular, epididymal, and prostate tissues from cisplatin-induced toxicity, and improve some functional parameters in male albino rats. The study recommended further research, and we propose conducting a histological and physiological study to test the effectiveness of aqueous extracts of horny goat weed on liver and kidney tissues and other body organs. We also propose isolating the active components of horny goat weed roots and stems and studying their protective effects against the side effects of medicinal drugs. Further studies are also needed to determine the toxic effects of cisplatin on other organs, such as the liver, kidney, and lungs, and its effect on the pituitary gland, adrenal gland, and thyroid gland. The student received a grade of excellent