The College of Education for Pure Sciences discussed a doctoral thesis entitled: “A Study of the Effectiveness of Asparagus Extract on Doxorubicin-Induced Reproductive Toxicity.”
The College of Education for Pure Sciences discussed a doctoral thesis entitled: “A Study of the Effectiveness of Asparagus Extract on Doxorubicin-Induced Reproductive Toxicity.”
The College of Education for Pure Sciences discussed a doctoral thesis entitled: “A Study of the Effectiveness of Asparagus Extract on Doxorubicin-Induced Reproductive Toxicity.”
The Department of Biology at the College of Education for Pure Sciences at the University of Karbala discussed a master’s thesis entitled “A Study of the Effectiveness of Asparagus Extract on Doxorubicin-Induced Reproductive Toxicity in Male Albino Rats.”
The thesis was written by student Fadaa Abdul-Sada Adhab, under the supervision of Professor Dr. Rasha Abdul-Amir Jawad.
The discussion was attended by Professor Dr. Sabah Wajid Ali, President of the University of Karbala.
The study aimed to investigate the protective effect of an alcoholic and nano-based extract of Asparagus officinalis loaded with zinc oxide against doxorubicin-induced reproductive toxicity in male albino rats (Rattus rattus) by examining some physiological parameters and histological changes in the testes and epididymis.
The study concluded that the alcoholic extract of asparagus contains biologically active compounds, including flavonoids, phenols, vitamins, minerals, and amino acids, which confer antioxidant and protective properties against the damage caused by doxorubicin. Furthermore, the alcoholic extract of asparagus possessed superior antioxidant activity at a concentration of 500 mg/kg compared to concentrations of 400 and 600 mg/kg, resulting in improved antioxidant activity, increased levels of reproductive hormones, positive sperm parameters, and good lipids, while reducing oxidants and harmful lipids.
The study recommended studying the effects of the active compounds of asparagus independently to determine their preventive and therapeutic effects on the male reproductive system. Studies should also be conducted to evaluate potential interactions between asparagus extracts and doxorubicin or other medications taken by cancer patients. The study also recommended evaluating the effectiveness of alcoholic and nano-asparagus extracts on the immune and endocrine systems. The student received an excellent grade.
