A lecturer from the Department of Biology at the College of Education for Pure Sciences publishes scientific research in an international journal.
The lecturer (Assistant Professor Dhu al-Fiqar Abbas Mutab) from the Department of Biology at the College of Education for Pure Sciences published a research entitled:
Circulating Levels of Human Fibroblast Growth Factor 21 are Associated with LDL in Patients with Coronary Artery Disease
In the Journal of Science in Medicine and Life
The research aimed to confirm whether the circulating levels of HFGF21 and LDL-lipid subsets are related. And how an enzyme called “HFGF21” degrades low-density lipoprotein receptors (LDL-R) in hepatocytes. Inhibition of HFGF21 has emerged as a new target for lipid-lowering drugs. Three different types of monocytes are essential to the pathophysiology of atherosclerosis.
The study included 70 people with coronary artery disease for the study. HFGF21 and LDL-lipid levels were measured in 30 healthy controls.
The study found that 80 percent of the cases involved men aged 40 to 70. Compared with 30 male controls, the patients had higher levels of HFGF21. CM was associated with circulating HFGF21 levels in the patients, but NCM was inversely associated with these levels. Individuals with above-average HFGF21 levels had significantly higher levels
