Discussion of a Master’s Thesis

The Department of Life Sciences at the College of Education for Pure Sciences at the University of Karbala discussed a master’s thesis entitled (Evaluation of the Effectiveness of the Aqueous Extract of Bandicoot Leaves (Lea indica) on some Physiological and Histological Parameters in Male Rats Treated with Diethylnitrosamine (DEN)) by the student (Mustafa Abdel Hussein Kadhom), and under the supervision of (A. M.D. Heba Alwan Abdel Salam).

The aim of the thesis was to study the effect of DEN on some functional liver enzymes (AST, ALT, ALP, T-Bil) and kidney function parameters (urea, uric acid, albumin and Creatinin), and to study the protective role of the aqueous extract of bandicoot berry leaves against induced oxidative stress. With DEN, and studying the histological heterogeneity caused by DEN in liver and kidney tissue.The message also included a defect in liver function through a significant increase in the concentration of ALT, ALP, AST, MDA, and T-BIL, and a defect in kidney function through a significant increase in Uric acid, Urea, Creatinine, EPO, and Renin and a significant decrease. In the average concentration of albumin and calciterol, and the appearance of clear tumor nodules in both liver and kidney tissue.

The thesis recommended using bandicoot berries as a preventive substance to reduce the possibility of liver and kidney cancer, studying the preventive and therapeutic effect of the alcoholic extract on autoimmune diseases such as acute intestinal inflammation and autoimmune myocarditis, and increasing awareness and education through interest in herbal medicine to reduce the resulting side effects. About chemical drug treatments. The student received an excellent grade.