The Department of Biology discusses a PhD thesis on the diagnosis of some types of yeast Candida spp. isolated from patients and the possibility of its inhibition using biologically manufactured Nanoparticles
The Department of Biology discusses a PhD thesis on the diagnosis of some types of yeast Candida spp. isolated from patients and the possibility of its inhibition using biologically manufactured Nanoparticles
The Department of Life Sciences at the College of Education for Pure Sciences, University of Karbala, discussed the doctoral dissertation entitled (Diagnosing some types of Candida spp. isolated from patients and the possibility of inhibiting them using biologically manufactured nanoparticles) by the student (Suhad Khalid Sagheer), and under the supervision of (Professor Dr. Ban Taha Muhammad). And (Prof. Dr. Ali Tariq Abdel Hassan). The thesis aimed to isolate some species of the genus Candida spp. From some hospitals in Karbala governorate and the diagnosis of some types of Candida spp. Biochemically and molecularly by knowing the sequence of the nitrogenous bases of the ITS gene and drawing the genetic relationship between the isolated species. Evaluation of the effectiveness of some antifungals on some types of Candida genus. The thesis also showed that the most age groups affected by candidiasis are 20-30 years old and 60-70 years old. It explained the diagnosis of Candida species on chromogenic agar media, and also showed the results of the percentage of the appearance of Candida species, which outweighed C. albicans with a number of 59 isolates, with a percentage of 63.4%, followed by C. glabrata with 14 isolates, with a rate of 15%. The thesis came out with several recommendations, including: Studying candidiasis for specific chronic diseases such as diabetes, high blood pressure, cancer, acquired immune diseases, and others in order to know the extent of infection and spread of these candida in each disease separately, and molecular diagnosis at the level of genes responsible for virulence factors in the yeast C. albicans in order to find a way to stop the gene expression of these genes. And evaluate the side effects of biologically manufactured nanomaterials through laboratory animal experiments. The student obtained the distinction.
