The Department of Biology Discusses a Master’s Thesis on Studying the Effect of an Aqueous Extract of Ginseng on some Physiological and Histological Parameters in Male Rabbits Treated with Lead Acetate

Discussion of a Master’s Thesis

The Department of biology at the College of Education for Pure Sciences discussed the master’s thesis for the student (Sarah Ali Hamza Saeed) entitled (Studying the effect of the aqueous extract of Panax ginseng on some physiological and histological parameters in male rabbits treated with lead acetate) under the supervision of Prof. Dr. Rasha Abdel Amir Jawad. . The study aimed to:
The focus of the physiological study:
1- Measurement of blood parameters (red blood cells, white blood cells, and hemoglobin)
2- Measuring some biochemical parameters (blood sugar, total cholesterol, triglycerides, high-density lipoproteins, and low-density lipoproteins).
3- Measuring some hormonal parameters (testosterone, luteinizing hormone, and follicle-stimulating hormone), as well as sperm concentration.
4- Measuring some parameters of oxidative stress, Malondialdehyde (MDA) oxidant, and some parameters of Glutathione (GSH) anti-oxidant parameter

* The focus of the histological study:-
1- Studying the testicular tissue and measuring the average diameters of the seminiferous tubules, the lumen, and the height of the epithelium, as well as measuring the average diameters of each of the cells (sperm progenitors, progenitor cells, spermatoblasts, and Sertoli cells).
2- Study of the epididymis tissue (measuring the average diameter of the epididymis and the lumen and the height of the epididymis of the head and tail of the epididymis).

As for the main conclusions:
The results of the current study concluded that oral administration of an aqueous extract of ginseng and lead acetate led physiologically and histologically to:
1- The aqueous extract of ginseng contains effective compounds that help in increasing the levels of male sex hormones and the concentration of sperm.
2- Ginseng roots contain antioxidant properties that help support the antioxidant defense system in the body and reduce lipid peroxidation and oxidants.
3- Ginseng has therapeutic properties that help preserve the testicular tissue from damage due to exposure to lead.
4 – Lead exposure leads to harmful effects on male sex hormones.
5- It was found that the aqueous extract of ginseng at a concentration of 600 mg/kg had the strongest effect in reducing the effects of the toxic substance (lead acetate) on physiological and histological parameters.
After extensive scientific discussion and listening to the student’s defense of her thesis, her research method, and her use of sources and references, the thesis was approved with honors. Congratulations to the student, her supervisor, the College of Education for Pure Sciences, and the University of Karbala for this achievement, and God Almighty grants success and payment.