The Department of Biology Discusses a Master Thesis on the Study of the Protective Role of the Aqueous Extract of Marjoram Leaves on some Biochemical Parameters and on the Tissue of the Liver and Kidneys in White Rats Treated with Ciprofloxacin

Discussion of a Master’s Thesis

The Department of Biology at the College of Education for Pure Sciences discussed the master’s thesis for student (Zainab Hussein Azab) entitled (Studying the protective role of the aqueous extract of Organum Majorana leaves on some biochemical parameters and on liver and kidney tissue in white rats treated with ciprofloxacin), under the supervision of (Asst.Dr. Shaima Malik Yasser). The current study aimed to: evaluate the effect of the aqueous extract of Organum Majorana leaves in reducing the effect of liver and kidney damage caused by ciprofloxacin in male rats by studying biochemical and histological changes.
As for the main conclusions:
1. Oral administration of ciprofloxacin caused oxidative stress, as it caused tissue damage to the liver and kidney tissue, represented by changes in both hepatocytes and sinusoids.
2. Oxidative stress caused changes in some biochemical parameters represented by a significant increase in the level of liver enzymes AST, ALT, ALP, urea, creatinine, sodium, calcium and potassium.
* We conclude from the above that the aqueous extract of marjoram majorana leaves has antioxidant effects on both kidney and liver tissue by reducing free radical activity and oxidative stress, as well as improving some functional parameters caused by ciprofloxacin in liver and kidney tissues in male albino rats.
After extensive scientific discussion and listening to the student’s defense of her thesis, her research method, and her use of sources and references, the thesis was approved with honors. Congratulations to the student, her supervisor, the College of Education for Pure Sciences, and the University of Karbala for this achievement, and God Almighty grants success and payment.