A Lecturer from the Department of Chemistry Publishes a Scientific Article in the ACE Journal of Advance Research in Chemical Sciences

Scientific Article

Instructor (Dr. Jahan Hamid Abdel Amir) / Department of Chemistry published an article entitled (Histidine‐Rich Glycoprotein (HRG): A Systematic Review of Prevalence Studies), which was published in an international journal (ACE Journal of Advance Research in Chemical Sciences).
The article summarized that HRG is a glycoprotein (histidine-rich glycoprotein) that has the role of coagulation function. It is a step in the process of immune fibrinolysis. The nervous system and angiogenesis are produced by the liver and found in platelet granules and serum-free protein; Angiogenesis inhibits thrombospondin function and by binding to plasminogen and plasmin, promotes cell migration. In this substantive review, the putative multifunctional activities of HRG will be discussed with emphasis on recent findings that have led to its development as a major regulating area of ​​immune and vascular biology. According to ELISA, HRG is the most abundant blood plasma protein of all six types (41‐61% of total plasma proteins by weight). HRG appears to be a metal-binding protein that is widely distributed in the plasma of bivalves. In the future, HRG could be a prominent player and a potential target for cancer treatment.