Scientific Article
The teaching staff in the College of Education for Pure Sciences/Department of Life Sciences, Prof. Dr. (Ashwaq Kazem Obaid) obtained the acceptance to publish a scientific article tagged with the title (Preservatives and their impact on human health) by the Scientific Articles Committee at the Presidency of Karbala University after the article fulfilled all publication conditions. (Prof. Dr. Kawthar Abdel-Hussein Mahdi) mentioned that the marker CD68 Cluster Designation 68 is an intracellular glycoprotein called by other names such as Macrosialin and KP1, with a molecular weight of 110 kDa, and because of its intracellular location and predominantly within cytoplasmic granules such as internal bodies ( Endosomes) and Lysosomes, and due to its structural properties, it is a member of the Lysosomes Associated Membrane Proteins; LAMP family (Gottfried et al., 2008). CD68 is the traditional immunohistochemical marker specific for macrophages and mononuclear cells, but it has recently been identified as a surface marker for neutrophils. In pluripotent T cells, natural killer cells, and non-blood tissues such as liver and renal tubules (Amanzada et al., 2013), as well as its expression in many types of tumor cells, this protein allows these cells to adhere to selectins and lectins molecules of vascular endothelial cells, which facilitates the Tumor spread to secondary sites, as Al-Saadi (2014) pointed out the important role of CD68 protein in tumor formation and inflammation as an initiating factor for inflammation in colorectal cancer.
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