The Associate Dean for Scientific Affairs Publishes a Scientific Article on the Preparation of New Pharmaceutical Polymers with a Three-Dimensional Network as a Drug Delivery System
The Associate Dean for Scientific Affairs Publishes a Scientific Article on the Preparation of New Pharmaceutical Polymers with a Three-Dimensional Network as a Drug Delivery System
The Associate Dean for Scientific Affairs at the College of Education for Pure Sciences, Prof. Dr. (Mohammed Nazem Bahjat) has accepted the publication of a tagged scientific article entitled (Preparation of New Pharmaceutical Polymers with a Three-Dimensional Network as a Drug Delivery System) by the Scientific Articles Committee at the Presidency of the University of Karbala Publication Terms. (Prof. Dr. Muhammad Nazem Bahgat) stated that over the past few decades, the gel polymer has achieved great development due to the development in the technical field, which led to its use in many biomedical applications, including controlled release, as there are Many researches on gel polymers, which were designed on the basis of protein delivery, due to the increasing medical and pharmaceutical needs, where mathematical modeling plays an important role in facilitating the design of the gel polymer network, by defining the basic parameters and molecule release mechanisms. The gel polymer is a polymeric network that absorbs water in large quantities and is insoluble in water, due to the chemical entanglement of the polymeric chains, and is able to maintain its three-dimensional structure in a distinctive way, so they are called hydrophilic gel polymers, and they have unique physical properties that made them useful For biological applications, including protein delivery, and it is one of the first compounds designed for medical use at an early age, many researches were conducted on the gel polymer aimed at developing it, and the methods of developing gel polymers have varied, so a modification has been made to the design and formation of biological polymers and gel polymers. Controlled liberation sensor and then used in practical applications. The reason for the success of gel polymers in these applications is due to their compatibility with biological methods, and the strength of their soft nature, as these properties make gel polymers similar to biological tissues and prevent cell deterioration, moreover, their ability to absorb water facilitates the establishment of cells or water molecules of proteins and peptides within the network Polymeric. The gel polymer has many medical uses, such as in the field of ophthalmology, where it was used in the preparation of contact lenses and also used in the treatment of perforated eardrums, as it is used as a cover for perforated eardrums, as well as in plastic surgery and in the field of protein delivery, which led to great progress in biology. Molecular biotechnology and biotechnology lead to mass production of protein therapies. Gel polymers release protein at the right time, at the right site, and at the right dose. The double value of the gel polymer’s potency helps improve proper protein delivery and maintain patient comfort and safety To use the gel polymer, the proteins are well presented and the encapsulated protein is released using a . method It is controlled over a long period of time. When the level of release is increased, it can be reduced automatically and in a controlled manner, thus maintaining the protein concentration at an optimum level for the longest possible period of time. Pharmaceutical gel polymers consist of large molecules consisting of several thousand atoms that form a three-dimensional network ((3D). They are used as effective therapeutic agents, are non-toxic and have greater selectivity. Pharmaceutical polymers are becoming increasingly important in pharmaceutical applications, especially in the field of drug delivery. They are used to mask the taste The pellet of the drug and to enhance the stability of the drug and also to extend the life of drug release, was also used as a means to regulate the secretion and then the body absorb some drugs as the drug is coated with a thin layer of this polymer that slowly decomposes, allowing the drug to be secreted inside the body according to a specific time mechanism and thus the polymer acts as a system for carrying and delivering drugs Pharmaceutical polymers have also been characterized by targeting infected cells and tissues without causing collateral damage and can be removed through metabolic pathways and excreted outside the body, taken orally, skin and inhaled, and some of these polymers can be used with high efficiency to treat cancerous tumors by closing the tiny capillaries that It nourishes cancerous tumors, and after a certain period of time the polymer decomposes and gets out of the body, but after it establishes an effective blockade. Except on the tumor, the polymer was also used as an effective drug through the development of polymeric drugs to isolate the varieties with low molecular weights such as bile acids, phosphates and iron, in addition to their multivalent interactions to restrict toxins, viruses and bacteria. Polymers are currently used in many medical fields, including pharmacological release systems. The most important problems associated with taking drugs can be solved through the technique of drug release systems, through which the concentration of the drug in the tissues of the body is controlled, as the drug compositions are carried on the polymeric network and the substance is transferred The active ingredient or the drug is transferred to the tissues of the body by a equilibrium action determined by the body’s need, and thus its concentration remains relatively constant and for a relatively long period of time.
