The respected Mrs. Dean of the College of Education for Pure Sciences, Dr. (Hamida Idan Salman), obtained the acceptance to publish a scientific article entitled (Adsorption of proteins on the surfaces of nanoparticles) by the Scientific Articles Committee at the Presidency of the University of Karbala, after the article fulfilled all publication conditions. The Dean mentioned that adsorption is the process of accumulating atoms or molecules of a substance, which may be a liquid or a gas, which is the substance (adsorbent), on the surface of another substance (adsorbent). This process can be done in different systems such as gas-liquid, liquid-liquid, liquid-solid and gas-solid. One example of the adsorption process is the adsorption of biological materials such as proteins, where the biophysical mechanism of protein adsorption is of great importance, because the adsorption proteins control biological reactions as they mediate, stimulate or mitigate the biological response to substances. Protein adsorption is a complex phenomenon for several reasons, as proteins are relatively large electrolytes that have adsorption properties that depend on a number of interrelated factors such as (size, shape and type of protein as well as structure and molecular weight of the protein, etc..), the interaction time between the protein and the surface, Surface chemistry and solution concentration also influence protein adsorption. Thus, protein adsorption faces multiple problems in surface physical chemistry. As a result of these factors, the analytical methods used to study protein adsorption have been varied and varied, and it has proven difficult to identify the generalities underlying protein adsorption. Proteins can adsorb to the surfaces of nanomaterials, which affects the adsorbed protein. The surface topography of nanocomposites has an effect on protein adsorption, and it is important to understand and control the interaction (chemical, physical) between nanostructured surfaces and proteins, especially for biomedical applications. Adsorption depends on the surface roughness, surface chemistry and the concentration of the adsorbed proteins. Nanoparticles cause changes in the structure of the adsorbed proteins, and they can alter the protein structure and thus affect the function of the adsorbed protein and affect the overall biological activity. Curved nanoparticle surfaces compared to flat surfaces provide additional flexibility and improved surface area for the adsorbed protein particles.
